“My research focuses on the genetic manipulation of CAR-T cells, an advanced form of cellular immunotherapy used in cancer treatment. By applying genome-editing technologies, I aim to understand how specific genes regulate CAR-T cell survival, proliferation, and functional persistence. Through systematic genetic screening and targeted gene-editing approaches, my work seeks to identify key genetic factors that influence CAR-T cell performance and long-term activity.
A central objective of my research is to improve the durability and therapeutic efficacy of CAR-T cells. By integrating molecular biology, immunology, and functional genomics, I investigate how genetic perturbations affect T-cell signaling, activation states, and phenotypic characteristics. This work contributes to a deeper mechanistic understanding of engineered immune cells and supports the development of more effective next-generation cell therapies.
In addition to laboratory research, I actively engage in international academic exchange and interdisciplinary communication. Interacting with researchers from diverse scientific backgrounds allows me to broaden my research perspective and explore innovative strategies beyond a single field. Through global collaboration and knowledge exchange, I aim to expand the translational impact of my research and contribute to the continued advancement of CAR-T cell–based immunotherapies for patients worldwide.”