医学研究科 施 ジユエ

Effect of mast cells on myopia progression

My name is Shi Jue, and I am currently a second-year student of Ph.D. in the photobiology lab, department of Ophthalmology, Keio University. My research focuses on the relationship between immune cells in the choroid and myopia development. Until now, the experiment results have shown that degranulation of immune cells on the choroid releases pro-inflammatory factors, leading to inflammation of the choroid and ultimately cause myopia development. Some immune cell stabilizers or inhibitors enable to inhibit the development of myopia by inhibiting axial length elongation. Because there are a lot of immune cells in the choroid, in the future study, I am going to focus on the choroidal microenvironment and want to summarize the effects of every immune cell on myopia development.