I am a PhD student in anesthesiology at Keio University, working with OxyBLI technology to investigate neurovascular and metabolic dynamics in the brain. My research focuses on how surgical stress and inflammation affect cerebral oxygenation and neural activity. By combining advanced optical imaging with disease models, I aim to uncover mechanisms of brain dysfunction and contribute to the development of monitoring and therapeutic strategies for perioperative care.

小児脳腫瘍は小児の病気による死因の第一位であり、新規治療法の開発が必要です。小児脳腫瘍において、腫瘍微小環境に存在する神経細胞が腫瘍細胞にもたらす電気的活動とエピゲノム変化の関係性を検証し、それに伴う腫瘍進展メカニズムを解明します。さらには微小環境に対する新たな治療標的を探索します。将来的には海外留学も経験し、Physician Scientistとして日本の小児脳腫瘍の臨床・研究を大きく進歩させることを志しています。

I am a graduate researcher at Keio University School of Medicine, focusing on gut microbiota–derived metabolites and their roles in intestinal homeostasis. My research centers on phenyl propionic acid (PPA), a microbial metabolite that enhances colonization resistance against pathogens through metabolic modulation rather than direct toxicity. By integrating gnotobiotic mouse models, molecular biology, and LC–MS–based metabolomics, I aim to uncover how microbiota-derived metabolites regulate host–microbe interactions. Ultimately, I seek to translate these findings into strategies for disease prevention and precision nutrition, contributing to a deeper understanding of how diet and microbiota shape human health.

小児科医として診療に携わりながら、育児アプリの記録データを用いて乳児期の栄養と成長の関係を解析しています。特に高出生体重児の成長軌跡に着目し、家庭内で生じる栄養選択と成長の多様性を可視化することで、乳幼児健診・保健指導・臨床支援を横断する新たな意思決定基盤の構築を目指します。経験に依存してきた成長評価と説明をデータに基づく共通言語へと再構築し、子育て家庭が納得して選択できる医療の実現に貢献します。

My research aims to elucidate how the gut microbiota influences the host nervous system by focusing on interactions between gut bacteria and the enteric nervous system (ENS), and investigating how these interactions relates to the central and peripheral nervous systems. By examining these mechanisms at both molecular and neural circuit levels, I seek to advance understanding of the gut-brain axis. Ultimately, this work aims to provide foundational insights into how microbiota-based interventions could contribute to novel therapeutic strategies for gastrointestinal and neurological diseases.

My research focuses on identifying novel therapeutic strategies for skin diseases, combining cellular and molecular approaches to better understand disease mechanisms and develop targeted interventions. I am particularly interested in translating these findings into practical applications within the skincare industry. In the future, I aim to contribute to product formulation in a skincare company, leveraging scientific insights to develop effective, evidence-based treatments that improve skin health and alleviate current socioeconomic burdens related to skin diseases.